Apoptosis in Cardiac Biology - download pdf or read online

By Jürgen Holtz M.D., Dorothea Darmer Ph.D. (auth.), Heribert Schunkert, G. A. J. Riegger (eds.)

ISBN-10: 0585381437

ISBN-13: 9780585381435

ISBN-10: 0792386485

ISBN-13: 9780792386483

Apoptosis or programmed cellphone demise is more and more thought of to be a significant component within the improvement and development of heart problems. In sufferers with middle failure the activation of apoptosis can result within the lack of irreplaceable cardiac myocytes selling the medical process the syndrome. furthermore, within the coronary arteries irritation and apoptosis may possibly weaken severe buildings of the vessel wall resulting in plaque rupture and, hence, to myocardial infarction. Given those deleterious results, it kind of feels virtually paradoxical that programmed telephone dying is an energetic approach that, if initiated less than physiological conditions, is vital for either coordinated tissue progress or destruction of malignant cells.
Apoptosis in Cardiac Biology, written via a group of the world over popular researchers, provides a well timed synopsis of uncomplicated mechanisms, mobile and structural goals and, eventually, medical implications of programmed phone loss of life within the center. The professional authors of this quantity supply concise overviews on common and cell-specific points of programmed phone loss of life in cardiac myocytes and fibroblasts, in addition to in vascular gentle muscle and endothelial cells. moreover, novel healing thoughts coming up from the exceptional pathophysiological value of cardiac apoptosis are offered.
This complete evaluation of Apoptosis in Cardiac Biology may be of curiosity to either clinicians and uncomplicated researchers who're energetic within the fields of cardiology and atherosclerosis.

Show description

Read Online or Download Apoptosis in Cardiac Biology PDF

Similar biology books

Download e-book for kindle: Organelle Proteomics by Edein P. Romijn, John R. Yates III (auth.), Delphine

Proteomic analyses have confirmed to be a useful instrument in acquiring high-throughput protein identity from low-abundance, complicated organic samples. In Organelle Proteomics, designated protocols offer step by step directions to effectively research organelle proteomes by means of acting the purification of a few of the organelles found in eukaryotic cells, in addition to by way of getting ready convinced sub-fractions of organelles.

Molecular Biology of Acute Lung Injury - download pdf or read online

Acute lung harm (ALI) affects sufferer care in each ICU on the planet. Our collective figuring out of this has grown immensely during the last decade yet morbidity and mortality stay unacceptably excessive. to augment the knowledge of clinicians and researchers, this ebook addresses the pathophysiology of acute lung damage from a molecular and mobile point of view; contains animal versions of acute lung damage and issues to strength healing advances in accordance with clinical findings.

Get Malignant Lymphomas: Biology and Treatment: An Update PDF

Within the previous couple of years a great deal of details concerning the biology and remedy of malignant lymphomas has been accrued and released in journals and monographs. there's, despite the fact that, no booklet that provides a concise and goal replace of this data or provides a normal survey of the topic.

Additional resources for Apoptosis in Cardiac Biology

Sample text

J. Koopman, and J. D. Mountz. Characterization of human Fas gene: exon/ intron organization and promoter region. J Immunol 154: 1239-1245, 1995. , P. R. Bourdon, H. Xu, Y. M. Hsu, H. Scott, C. Hession, I. Garcia, and J. L. Browning. TWEAK, a new secreted ligand in the tumor necrosis factor family that weakly induces apoptosis. JBiol Chem 272: 32401-32410, 1997. Chinnaiyan, A. , 0 . R. K, G. L. Yu, R. H. Lyons, M. Garg, D. R. Duan, L. Xing, R. Gentz, J. Ni, and V. M. Dixit. Signal transduction by DR3, a death domain-containing receptor related to TNFR- 1 and CD95.

Donahue, S. W. Shenvood, A. L. Gurney, K. J. Hillan, R. L. Cohen, A. D. Goddard, D. Botstein, and A. Ashkenazi. Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer. Nature 396: 699-703, 1998. Pitti, R. , S. A. Marsters, S. Ruppert, C. J. Donahue, A. Moore, and A. Ashkenazi. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 271 : 12687-12690, 1996. Ruoslahti, E. RGD and other recognition sequences for integrins.

Wyche, and E. A. Hendrickson. A cytosolic factor is required for rnitochondrial cytochrome c efflux during apoptosis. Cell Death D g 5 : 469-479, 1998. , F. L. Rock, S. Balasubramanian, R. A. Kastelein, and J. F. Bazan. Molecular characterization and modular analysis of human MyD88. Oncogene 13: 2467-2475, 1996. , G. Papoff, A. Eramo, K. Reif, C. D. , and G. Ruberti, Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B. Eur J Immunol28: 57-69, 1998.

Download PDF sample

Apoptosis in Cardiac Biology by Jürgen Holtz M.D., Dorothea Darmer Ph.D. (auth.), Heribert Schunkert, G. A. J. Riegger (eds.)

by George

Rated 4.33 of 5 – based on 20 votes